Exploring New Possibilities with Biomedical Simulation

Exploring New Possibilities with Biomedical Simulation

Exploring New Possibilities with Biomedical Simulation

Biomedical engineering continues to offer amazing solutions to the medical community using sophisticated designs at the nano level. This is well demonstrated in the fabrication of membranes and human tissue that are now developed and designed using complex simulation technology.

Simulation is a very useful capability of modern engineering. Everything from fluid systems to automobiles, cities, transit systems, spacecraft, and ocean-going ships can all be studied and analyzed through advanced simulation and modeling. When technology is successfully applied to simulation in one area of biomedical engineering, for example, it may well be applied to another area. Once cell and tissue growth is understood for one organ, it may possibly help understand growth in another organ, and assist in the creation of artificial tissues and organs moving forward. We are seeing the application of simulation to human systems already, for example, at Stanford University – where in 2020 researchers simulated the hidden pattern that drives brain growth. Researchers say that similar rules could guide the development of other cells within the body and understanding them could be important for successfully bioengineering artificial tissues and organs.

Advancing Medical Simulation Within a Cell

The University of Groningen in Groningen, Netherlands has advanced tissue simulation by creating an algorithm that helps them to utilize finite data about the tissue and simulate complex geometries such as membrane curvatures. Their algorithm allows different resolutions to be combined to create very accurate depictions for study and simulation. The researchers were able to accurately model and simulate a full-sized mitochondrial lipid membrane. This also allowed them to reverse engineer a larger scale tissue model for study and further exploration.

The researchers hope to apply their advancements in simulation to one day successfully create a synthetic cell. While the parts of a cell are so tiny that it is not possible to successfully simulate them, the progress they’ve made gives hope for further scientific study and research that may be used to find solutions to other complex biological problems.

Exploring New Possibilities with Biomedical Simulation

Biomedical simulation is at the forefront of progress for medical research. That which can be simulated serves as the basis for iterations that may lead to breakthrough solutions to medical problems otherwise thought impossible. When organs, tissue, and biological systems within the human body can actually be simulated, trial and error—a hallmark of the scientific method and the advancement of medicine—is greatly facilitated.

Take the human heart, for example. Using engineering simulation software, a model of a healthy human heart with all four chambers and its vascular pathways of arteries, veins, and blood flow, can be realistically and accurately depicted. From an engineering perspective – the heart is regulated by factors such as electrical signals, its structure, and the physics of fluid flowing intricately within it. All these factors may be fed into the simulation software to create a complete and comprehensive characterization of the cardiac tissue, right down to its fibrous structure, electrical pathways, and expected performance and behavior. From there, researchers can explore different effects on the heart and its performance using various changes and stimuli.

For example, an accurate simulation of the heart may greatly aid stent design and placement. Nearly half a million stents are placed in patients annually to provide a clearer pathway for critical blood flow. A stent must be able to last at least 10 years; just over one third of those who have a stent implanted will have to have it re-implanted over their lifetime.

By simulating the human heart, along with blood and fluid circulation, stent design may be improved to account for design factors such as strength, structural fatigue life and limits of the implanted stent, and inclusion of variables that improve the stent’s reliability.

Tools to Advance

Simulation tools and software are applicable in many genres of science and engineering. On the biomedical front, they are especially helpful as the human body does not lend itself to snafus and error. Yet, with accurate simulation, many things may be tried before arriving at successful solutions such as a stent, or the treatment of a biological system with a complex tissue structure within its organs.

Simulation provides medical researchers and physicians with new tools to explore new possibilities, and ultimately arrive at new and productive solutions in medicine, now and into the future.

For more information concerning our portfolio of Simulation software solutions, contact a Mecanica Solutions specialist. Original post from ww.3DS.com.

The Race to Market for Urban Air Mobility

The Race to Market for Urban Air Mobility

The coronavirus pandemic may have cooled the hype, but it hasn’t dampened the enthusiasm in the nascent urban air mobility (UAM) sector. Testing of electric vertical-and-takeoff-and-landing (eVTOL) vehicles is picking up pace, and the first type certifications and commercial deliveries could start in less than three years. The race to be the first to market is heating up.

In the U.S., Joby Aviation is transitioning to a company focused less on development and more on certification, initial manufacturing and laying the groundwork for 

commercial operations of its pioneering air taxi design. In Germany, Volocopter, having recently completed successful demonstration flights of its “VoloCity” aircraft in 

Helsinki and Singapore, has started  selling tickets for limited reservation flights to help fund continued development and certification. And in the U.K., Vertical Aerospace recently released its air taxi design called the VA-1X, which the company expects to certify and put into commercial operation by 2024

All of this momentum stands in sharp contrast to the commercial aviation sector, where airline passenger volume is down by more than half from last year. In the U.S., it’s about 70 percent of what it was in 2019, according to Washington, D.C.-based Airlines for America, the industry’s principal trade organization.

As if that weren’t bad enough, near-term prospects point to only modest improvements, and new Aviation Week Intelligence Network data suggests the demand for new aircraft production could be about 30 percent lower over the next 10 years than previously thought.

First-wave UAM companies moving through prototyping and certification are fleshing out business plans that are not all focused on inner-city transportation. Intercity flights, first responders, medical deliveries and unmanned logistics also are in the emerging market mix.

Joby is on track for certification in 2023. Designated the S4 for certification purposes, the yet-to-be-named air taxi is configured to carry four passengers and one pilot. It will be capable of operating day and night in instrument or visual flight rules up to 150 nautical miles. Driven by the goals safety, noise abatement and affordability, a Joby Aviation official said the design is about 100 times quieter than a helicopter.

The company has completed several hundred flights of its second-generation high-wing, six-propeller “2.0” version since 2019, including some with a pilot onboard. The aircraft features multiple redundancy in power and control surfaces.

Subscale S4 prototypes have been flown more than 700 times, starting in 2015. “The No. 1 priority is safety, and at a level you see in commercial aviation, which is the safest mode of travel we have,” CEO and Chief Engineer JoeBen Bevirt said.

For its part, Vertical Aerospace plans to forego subscale prototyping and proceed directly to full-scale production in order to meet its 2024 certification goal. It’s currently working with suppliers such as avionics provider Honeywell, to test individual systems. “The VA-X1 is an important technical milestone for the UAM industry,” said Stephane Fymat, vice president and general manager of Urban Air Mobility and Unmanned Aerial Systems at Honeywell

Dassault Systèmes will furnish the Product Lifecycle Management software to Vertical Aerospace through its cloud-based 3DEXPERIENCE platform.

VA-1X will have a more complex design that will feature numerous control surfaces and vectored thrust that’s likely to be more challenging to certify but may have more transport applications than an earlier design that employed no fewer than 12 overhead propellers in a multirotor configuration. Thrust vectoring is the ability of an aircraft to manipulate the direction of engine thrust to control its attitude or angular velocity.

The aircraft will have a range of up to 100 nautical miles and a maximum cruising speed of 150 miles per hour. Like Joby’s S4, the VA-1X will be certified to the same safety standards as commercial airliners, according to Vertical CEO Michael Cervenka. In addition, it will be optimized for longer-range flights to take advantage of the tiltrotor’s efficient cruise. The VA-1X is designed to connect entire regions, as well as flying shorter missions within metropolitan areas.

This original post was published on the Dassault Systèmes Blog : https://blogs.3ds.com/northamerica/the-race-to-market-for-urban-air-mobility/

Shaping the future of work with 3DEXPERIENCE

Shaping the future of work with 3DEXPERIENCE

Shaping the future of work with 3DEXPERIENCE

The World Economic Forum has projected that 65% of children currently in primary school will hold jobs that currently don’t exist. While those students are still a few decades from entering the workforce, there is a related challenge upon us today: university students and seasoned professionals alike are finding themselves lacking the job skills currently in demand by industry. This is particularly true for the many companies focused on creating sustainable innovation, which is calling for new technology and new approaches to ideation.

For years, studies have pointed to a gap between the skills needed to fill vacant jobs and what is being taught in schools. Industry disruption from the COVID-19 pandemic became a proof point of this for chasm; as companies needed to quickly pivot to redefine their business model, it became clear how much reskilling, upskilling and training is needed. Roles are evovling fast. Industry alone can’t make overcome this challenge: academic institutions must also transform their approach to what they teach, and how, now that hybrid learning is becoming the new norm.

To help shape the workforce of the future, we have launched 3DEXPERIENCE Edu, a new Dassault Systèmes world to empower people with the right skills to create a more sustainable future! 3DEXPERIENCE Edu is designed to help students and professionals thrive in the workplace with in-demand skills. It also will connect academic institutions with businesses to redefine how they can work together to identify needs and training methods. The goal is to boost employability by reducing the gap between industry needs and what is taught in classes.

3DEXPERIENCE Edu will also continue the Dassault Systèmes tradition of offering challenges and competitions for hands-on learning. Experience-based learning is growing in popularity, and helps people actively grow both hard and soft skills. You can see current and past challenges here.

To work on these challenges and provide first-hand know-how, the program also offers students access to software throughout the year. Through November 6, in celebration of back to school, students can request one year of free access to the 3DEXPERIENCE platform through 3DEXPERIENCE Engineer based on CATIA or 3D Designer based on SOLIDWORKS. Interested students can learn more here.

3DEXPERIENCE Edu offers an inclusive world where excellence, individual performance and purpose combine with user communities to make learning fun and enjoyable for all. We look forward to sharing stories about how the different entities – students, academics, professionals and companies – are working through 3DEXPERIENCE Edu to be more agile and ready to take on – and create – what’s next. Stay tuned!

This original Blog was published on Dassault Systemes blog : https://blogs.3ds.com/perspectives/shaping-the-future-of-work-with-3dexperience/

Tackling pollution and transforming the car ownership experience

Tackling pollution and transforming the car ownership experience


In 2010, there were only around 17,000 electric cars on the world’s roads. By 2019, that number had swelled to 7.2 million, almost half of which were in China – the world’s largest automobile market. For China, electric vehicles (EVs) are one of 10 commercial sectors central to the government’s “Made in China” effort to boost advanced industrial technology. The government will provide billions of dollars to subsidize the manufacturing of EVs and batteries, and encouraging businesses and consumers to buy them.

Not only does China’s EV industry play to the government’s national ambitions, it’s also helping to solve some of the nation’s most pressing energy and environmental concerns as China continues to tackle high air pollution in its major cities and reduce its climate change emissions.

One of the leaders in China’s fledgling electric car industry is NIO, whose ambition is to make EVs the natural choice for everyone, leading to a more sustainable tomorrow. Hence the start-up’s Chinese name: Weilei, which translates as ‘blue sky coming.’

Since 2014, the company has been building a new generation of electric road cars that deliver superior performance and unique user experiences, backed by a vision to help consumers rediscover the ‘joyful lifestyle’ of car ownership. The company primarily serves the Chinese market, but from the very beginning has been committed to expanding its global reach. They needed a strong technology platform to support its growth. NIO decided on the 3DEXPERIENCE platform as the foundation for its enterprise-wide research and development activities.

Before implementing the 3DEXPERIENCE platform, NIO’s designers and engineers worked in siloes, focused only on their local product development activities. Now they all work collaboratively on a truly global development platform, which manages the company’s entire product development lifecycle, ensuring digital continuity, data integrity and effective change management at every stage of the process.

Crucially, NIO was able to move from concept to launch of its ES8 model in just three years, thanks to enhanced collaboration between its global teams and partners on the platform. With completely integrated design and manufacturing processes and accurate data, NIO can now focus on innovation as it continues to scale its business.

“The 3DEXPERIENCE platform drives our users’ creativity and promotes innovation by allowing them to work in 3D,” said Longyun Zou, associate director, digital engineering team & expert at NIO. “Having a single product design platform, coupled with synchronized engineering, significantly accelerates product design. This strong technology support certainly helped to accelerate the ES8’s time to market.”

Want to discover more about how NIO is taking advantage of the 3DEXPERIENCE platform to accelerate product development and grow its global presence? Watch the videos below or read the detailed case study.

This original artIcle has been published on the Dassault Systèmes’ blog: https://blogs.3ds.com/perspectives/tackling-pollution-and-transforming-the-car-ownership-experience/


Bringing South Korea’s smart construction vision to life

Bringing South Korea’s smart construction vision to life

The South Korean government is on a mission to bring cutting-edge technology to the construction industry. It’s part of an ambitious smart construction technology roadmap that will see the nation’s civil engineering businesses embrace a combination of cloud computing, building information modeling (BIM), the Internet of Things, big data, drones and robots as we enter a new chapter in human development driven by the Fourth Industrial Revolution.

For Dasan Consultants, this created a great opportunity to build the foundation for a new BIM design approach. The leading Korean engineering and consulting firm specializes in delivering planning, design and construction management services to the global transportation, land, water, environment, energy and plant sectors. Not only did it want to improve its competitive edge and grow its reputation as a national trailblazer, it also wanted to cut down on unnecessary costs while guaranteeing quality, reliability and sustainability.

The company turned to the 3DEXPERIENCE platform on cloud to drive its business-wide transformation and make the switch from 2D to 3D. Today, the platform serves as a centralized database to manage data and intellectual property, securely share information with all stakeholders and work on designs company wide, bringing all design and engineering units together. At the same time, Dasan can actively avoid the design errors, incoherence, interference and miscalculation that commonly crop up in traditional 2D drawings.

Dasan used the 3DEXPERIENCE platform to manage the Yangpyung-Icheon Expressway construction project with impressive results.

“This was the first time we used our new BIM design approach in a project,” said Kim Bong-Seok, director at Dasan Consultants. “Our client recognized the excellent quality of the civil engineering design, enabled by the 3DEXPERIENCE platform, and it meant that we were able to win the next project as well.”

Want to learn more about how Dasan is building on its leading reputation and using the 3DEXPERIENCE platform to make 3D BIM a reality? Watch the videos below or read the detailed case study.

This original article was published on Dassault Systèmes’ blog: https://blogs.3ds.com/